Riding in the Yellow Submarine

alicelongbottem:

My coping mechanism for most things in life is to read or watch more Harry Potter.

raxenne:

Happy birthday, Harry Potter!

To celebrate Harry’s birthday (and my undying love for the series), I made my own covers! I created patterns (Thanks for the inspiration Scandinavia!) using a significant object from each book. I used those in the movies as reference and digitally painted them. You can view the whole project here! :)

(It’s already July 31 here in the Philippines. Haha.)

mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.
In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.
"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.



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mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.

In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.

"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.

edwardsheerran:

andthatlittleblackdress:

honestly sometimes in school people say the most ridiculous shit and I make this face and look somewhere at an imaginary camera like I’m on The Office

My school has security cameras in every classroom and I’ve done this at least 3 times each class this entire year. Today the security guard came up to me and told me I was his hero. 

mothernaturenetwork:

Muggle scientists develop Harry Potter ‘Marauder’s Map’ technologyAn algorithm developed at Carnegie Mellon University allows multiple individuals to be tracked in a complex environment even when they slip out of a camera’s view.

mothernaturenetwork:

Muggle scientists develop Harry Potter ‘Marauder’s Map’ technology
An algorithm developed at Carnegie Mellon University allows multiple individuals to be tracked in a complex environment even when they slip out of a camera’s view.

sherlscott:

Words of wisdom from Ron Swanson.

livingpursuit:


| House Between 2 Gardens in Israel | ©


| House Between 2 Gardens in Israel | ©

livingpursuit:

| House Between 2 Gardens in Israel | ©

| House Between 2 Gardens in Israel | ©

kimplz:

PROPHET LIKE IT’S HOT

kimplz:

PROPHET LIKE IT’S HOT


| R1T Apartment | © | More 

R1T Apartment | © | More 

laptopped:

do rude people know they’re rude

askfallencas:

watching yourself being replaced by people better than you

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wut-the-pho:

gameofchrons:

friend: “i can only bring one friend. wanna go?” 

me:

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E